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Addressing unhealthy lifestyles could increase life expectancy of those with severe mental illness

Interventions that aim to stop smoking among people with schizophrenia and approaches to lessen sedentary behavior among people with bipolar disorders appear to be the most promising ways to increase life expectancy, showing an increase of 2 years 5 months and an increase of one year 3 months, respectively.

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A study found that tackling unhealthy lifestyle factors would provide the greatest benefit in increasing life expectancy among those with severe mental illness (SMI). In particular, interventions that aim to stop smoking among people with schizophrenia and approaches to lessen sedentary behavior among people with bipolar disorders appear to be the most promising ways to increase life expectancy, showing an increase of 2 years 5 months and an increase of one year 3 months, respectively.

The results were noted by Alex Dregan et al. in “Potential gains in life expectancy from reducing amenable mortality among people diagnosed with serious mental illness in the United Kingdom“, published in PLOS ONE.

Currently, people with SMI tend to live on average 12 to 15 years less than those in the general population. 80% of deaths of those with SMI are caused by common diseases such as heart disease, respiratory illnesses, diabetes, cancer and digestive disorders. All these diseases can be partly attributed to unhealthy lifestyle factors, social isolation and deprivation, and inadequate use of healthcare services.

To inform public health policy, the study aimed to estimate how much tackling these changeable factors in the lives of people with SMI could translate into a gain in life expectancy.

Using data from systemic reviews, the researchers estimated the level of association between a range of different risk factors and the total number of deaths amongst those with SMI. The factors were categorized into three groups: behavioral risk factors such as smoking and physical inactivity, healthcare risk factors such as uptake of treatment and access to healthcare resources and social risk factors such as stigma and exclusion.

By considering the effectiveness of interventions aimed at changing these factors the researchers then calculated the gains in life expectancy that could occur. Examples of interventions to address the risk factors were smoking cessation initiatives, improving access to anti-psychotic medication and educative approaches to reduce stigma.

The analysis estimated that approaches that tackled all these factors could produce a potential gain in life expectancy from birth of four years for those with bipolar disorders and seven years for those with schizophrenia. Gains in life expectancies were also estimated later in life and at 65 years the projected gain was three years for bipolar disorder and four years for schizophrenia.

Lead author, Dregan from the Institute of Psychiatry, Psychology & Psychiatry, King’s College London, said: “Our study shows that by addressing the health behaviors, healthcare engagement and social issues of people with severe mental illness we could potentially increase their life expectancy by about 4 to 7 years. The analysis indicates that, when considering different approaches to help those with severe mental illness, the whole is greater than the sum of the parts and there is more benefit if a multi-faceted approach is taken which addresses behavior, healthcare and social issues simultaneously. Greater investments in developing more effective interventions aimed at reducing unhealthy behaviors and treating the underlying symptoms would contribute to reducing the gap in premature mortality between those with severe mental illness and the general population.”

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Mental health is a big issue in the LGBTQIA community.

In 2017, for instance, a study suggested that experiencing anti-bisexual prejudice, internalized heterosexism, and identity concealment appears to be related to feelings of loneliness and ultimately psychological distress and suicidality among bi individuals.

In 2019, a study found that sexual minorities were around five times more likely to experience high depressive symptoms (54% vs 15%) and self-harm (54% vs 14%). They also had lower life satisfaction (34% vs 10%), lower self-esteem and were more likely to experience all forms of bullying (i.e. peer bullying 27% vs 10%) and victimization (i.e. sexual assault/harassment 11% vs 3%) .

Efforts curbing SOGIESC of LGBTQIA people also affect their mental health.

For instance, a 2019 study noted that “conversion efforts” to try to change a person’s gender identity to match their sex assigned at birth were associated with increased likelihood of adverse mental health outcomes, including suicide attempts. These conversion efforts continue to be prevalent even now.

Also in 2019, a study found that among transgender individuals with gender incongruence, undergoing gender-affirming surgery was significantly associated with a decrease in mental health treatment over time.


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