Connect with us

Health & Wellness

Gender-affirming hormone therapy impacts results of lab tests for trans patients

The fact that many medical protocols do not account for sex/gender incongruence is a significant barrier for transgender individuals seeking healthcare.

Published

on

Photo by Mercedes Mehling from Unsplash.com

Gender-affirming hormone therapy markedly impacts the results of common laboratory tests for transgender patients. This is according to a study that underscores the need for transgender-specific reference intervals to ensure this underserved population receives accurate diagnoses and effective treatments.

The fact that many medical protocols do not account for sex/gender incongruence is a significant barrier for transgender individuals seeking healthcare. In particular, for the nearly 50% of transgender individuals on hormone therapy, the medical field has yet to define reference intervals, which are the ranges of test result values observed in a healthy population that are used to determine whether individual lab results are normal or concerning.

Without tailored reference intervals, test results for transgender patients on hormone therapy could indicate an underlying condition but go unrecognized if they are considered normal for cisgender individuals (those whose gender matches their assigned-at-birth sex). Conversely, if lab results for transgender patients fall outside of cisgender reference intervals, they could trigger unnecessary follow-up work even if the results are actually normal.

To help build the case for developing transgender reference intervals, a research team led by Jeff SoRelle, MD, of University of Texas Southwestern Medical Center in Dallas, investigated whether transgender patients on hormone therapy exhibit altered results for laboratory tests ordered during yearly check-ups. The study authors recorded lab values for a complete blood count, comprehensive metabolic panel, and lipid tests in 264 healthy transgender patients undergoing hormone therapy in transgender clinics from 2007 to 2017. Of these patients, 133 were taking estradiol to transition from male to female, and 89 were taking testosterone to transition from female to male. The scientists also gathered lab results for 149 transgender patients not undergoing hormone therapy to serve as a point of comparison.

READ:  HIV-positive and looking for a job

From this, the researchers determined that both transgender women and men taking hormones displayed altered values for measures of red blood cell, kidney, and liver health. Transgender women taking hormones also had altered sodium, calcium, total protein, glucose, and platelet levels, while transgender men taking hormones displayed altered lipid values. Interpretation of these altered test results in the context of cisgender reference intervals could have serious consequences, from preventing diagnosis of anemia or kidney disease to affecting assessment of cardiovascular disease risk.

“Transgender patients will need their own reference ranges for several important parameters such as hemoglobin and creatinine,” said SoRelle. “It will also be important to determine whether proteins from cardiac muscle or the prostate, such as troponins or prostate specific antigen, are altered, too, which could affect diagnosis of heart attacks and prostate cancer.”

Health & Wellness

Sexual minority women less likely to receive appropriate sexual, reproductive health support

A research emphasizes the importance of considering both sexual orientation and recent sexual behaviors when addressing the sexual and reproductive health needs of sexual minority women.

Published

on

Photo by @rawpixel from Unsplash.com

Lesbian women were less likely to report receiving a birth control prescription or birth control counseling compared with heterosexual women. This is according to a new study that used data from the National Survey of Family Growth 2006-2015 in the US, and which highlighted sexual and reproductive health care disparities among women.

In “Do Sexual Minorities Receive Appropriate Sexual and Reproductive Health Care and Counseling?”, Bethany Everett, PhD, University of Utah (Salt Lake City) and colleagues from the University of Wisconsin (Madison) and the University of Chicago (IL) investigated sexual orientation disparities in the use of sexual and reproductive health services and receipt of contraceptive counseling in clinical settings in the past 12 months.

The researchers also explored whether having male sex partners influenced sexual minority women’s use of sexual and reproductive health services and the types of sexual health information that they received.

The findings – published in Journal of Women’s Health, a peer-reviewed publication from Mary Ann Liebert, Inc. –  noted that in a clinical setting, lesbian women were less likely to report receiving birth control counseling at a pregnancy test, and lesbian women without recent male sex partners were less likely to report receiving counseling about condom use at an STI-related visit compared with heterosexual women.

However, they were more likely to report having received sexually transmitted infection (STI) counseling, testing, or treatment, after adjusting for sexual partners in the past 12 months.

“This new research emphasizes the importance of considering both sexual orientation and recent sexual behaviors when addressing the sexual and reproductive health needs of sexual minority women,” said Susan G. Kornstein, MD, editor in chief of Journal of Women’s Health and executive director of the Virginia Commonwealth University Institute for Women’s Health, Richmond, VA. “Using inclusive sexual and reproductive health counseling scripts may facilitate the delivery of appropriate sexual health-related information.”

READ:  Over 70% of APAC respondents think life should be fair

Continue Reading

Health & Wellness

Trauma increases heart disease risk in lesbians, bi women

Women were 30% more likely to suffer from anxiety if they experienced any forms of adulthood trauma and 41% more likely to be depressed if they faced childhood trauma.

Published

on

Photo by DESIGNECOLOGIST from Unsplash.com

Trauma, including abuse and neglect, is associated with higher cardiovascular disease risk for lesbian and bi women.

This is according to preliminary research presented in Chicago in the US, at the American Heart Association’s Scientific Sessions 2018, a global exchange of the latest advances in cardiovascular science for researchers and clinicians. The research – led by researchers from the Columbia University – showed that sexual minority women with increased severity of childhood, adulthood or lifetime trauma had higher risk for post traumatic stress disorder (PTSD) and a perception of less social support.

For this, the researchers studied 547 sexual minority women. They measured three forms of childhood trauma: physical abuse, sexual abuse and parental neglect; three forms of adult trauma: physical abuse, sexual abuse and intimate partner violence; and lifetime trauma, which was the sum of childhood and adulthood trauma. They analyzed how increasing trauma severity was associated with higher report of several cardiovascular risk factors.

They found that women were 30% more likely to suffer from anxiety if they experienced any forms of adulthood trauma and 41% more likely to be depressed if they faced childhood trauma.

Other findings included:

  • 22% more likely to be depressed if they had experienced more forms of lifetime trauma.
  • 44% more likely to report overeating in the past three months if they experienced increased forms of childhood trauma.
  • 58% more likely to have diabetes if they experienced increasing severity of childhood trauma, and lifetime trauma notably increased their risks of obesity and high blood pressure.
READ:  Top 10 vegan chocolate desserts in Manila

These findings suggest healthcare providers should screen for trauma as a cardiovascular disease risk factor in this population, according to the researchers.

The results were presented at the American Heart Association Scientific Sessions in Chicago.

The research was recognized as the “Cardiovascular Stroke Nursing Best Abstract Award.”

Continue Reading

Health & Wellness

Attitudes toward sexual minorities, HIV-positive people among physicians are changing

Research finds that there have been substantive declines over a 35-year period in the prevalence of stigmatizing attitudes toward sexual minorities and HIV-positive people among physician respondents.

Published

on

Photo by @rawpixel from Unsplash.com

Medical practitioners are among the sources of LGBT- and HIV-related discrimination; but this may be changing… even if slowly.

This is according to “Physician Attitudes Toward Homosexuality and HIV: The PATHH-III Survey“, a study by R. Marlin, A. Kadakia, B. Ethridge and W.C. Mathews, and published in LGBT Health.

The study eyed to (1) to evaluate current physician attitudes toward homosexuality and homosexual, transgender, and HIV-positive individuals; and (2) to compare current attitudes of those from prior surveys of the same population, the San Diego County medical community.

For this study, an online survey was conducted during November-December 2017 to assess general attitudes toward homosexuality and medically focused items that addressed homosexual orientation, transgender identity, and HIV. Responses were weighted for nonresponse. Predictors of stigma were assessed using generalized linear models. Trends across three surveys of the same population in 1982, 1999, and 2017 using common items were assessed using unweighted responses.

Of 4,418 physicians, 491 (11.1%) responded (median age 55 years, 38% female and 8.7% gay or bisexual). Regarding admission to medical school, 1% opposed admitting a homosexual applicant, 2% a transgender applicant, and 5% an HIV-positive applicant. Regarding consultative referral to a pediatrician, 3% would discontinue referral to a homosexual pediatrician, 5% to a transgender pediatrician, and 10% to an HIV-positive pediatrician. Regarding discomfort treating patients, 7% reported discomfort treating homosexual patients, 22% transgender patients, and 13% HIV-positive patients. Earlier year of graduation from medical school, male gender, and heterosexual orientation were significant predictors of stigma-associated responses.

READ:  US study reveals impact of marriage equality on wedding planning

Compared with the results from surveys in 1982 and 1999, the current results suggest substantively less stigma associated with homosexuality and HIV.

Even with health insurance, lesbian, gay and bi adults more likely to delay medical care

For the researchers, it is worth noting that – finally – “there have been substantive declines over a 35-year period in the prevalence of stigmatizing attitudes toward sexual minorities and HIV-positive people among physician respondents.”

There’s hope yet, after all.

Continue Reading

Health & Wellness

Family acceptance of LGBT identity linked to lower stress

According to the researchers, the family provides a foundation of support, and if those who identify as LGBT are comfortable disclosing to their family, they seem to have a protective stress profile.

Published

on

Image used for illustration purpose only; photo by Annie Spratt from Unsplash.com

Those who identify as LGBT and have come out to their family carry less stress hormones than those who have not come out, which may ultimately benefit their health. This is according to a study by Ohio University Associate Professor of Psychology Dr. Peggy Zoccola with Andrew Manigault M.S., published in the October issue of Psychosomatic Medicine, journal of the Psychosomatic Society.

The study eyed to discuss how feeling able to comfortably talk about your sexual identity with family members specifically, appears to be most linked to output of the stress hormone cortisol; a hormone that if too much is produced can damage an individual’s health.

For the study, Zoccola had 121 sexual minority adults ages 18 to 35 take a survey about their depression and anxiety levels, sociodemographic factors and how much support they felt. They were also asked how out they were to family, friends, acquaintances, coworkers and clergy in religious organizations, as well as provided their age when they came out. Following the survey, 58 individuals from the group were randomly selected to provide a saliva sample to show their cortisol levels.

The results of Zoccola’s research showed that the more open people were to disclosing their sexuality with their family, the lower cortisol levels they had.

“The real stress punch seems to be with the family,” said Zoccola when referencing how greater disclosure of a LGBT individual’s sexuality to their family is strongly linked to lower cortisol.  “For these emerging adults, the family provides a foundation of support… If they’re comfortable disclosing to their family, they seem to have a protective stress profile.”

READ:  The technical side of taking care of yourself isn’t as tough as you think

Zoccola said that there has been sparse research on how the aspects of coming out by LGBT adults affect the release of stress hormones; but earlier studies have shown that if people who identify as sexual minorities feel acceptance from their families, they have higher self-esteem, lower depression and substance use rates and are less likely to think about suicide.

Continue Reading

Health & Wellness

Trans youth lack access to trans-affirming care, which may put them at risk for HIV

One-quarter of youth were less inclined to discuss GSM (gender and sexual minority) identity and sexual health with their primary care providers due to concern that their provider would disclose this information to parents.

Published

on

Photo by Mercedes Mehling from Unsplash.com

Many trans youth lack access to trans affirming care, which may put them at risk for HIV. This is according to a study that explored trans youth’s perceptions regarding encounters with primary care providers (PCPs) related to gender and sexual minority (GSM) identity and sexual health.

In “Perceived Barriers to HIV Prevention Services for Transgender Youth”, which appeared in LGBT Health, C.B. Fisher, A.L. Fried, M. Desmond, K. Macapagal and B. Mustanski engaged youth aged 14-21 (N = 228; 45% trans masculine, 41% trans feminine, 14% gender nonbinary) and asked them to complete a survey on GSM identity disclosure and acceptance, gender-affirming services, sexual health attitudes and behaviors, and interactions with PCPs involving GSM identity and concerns about stigma and confidentiality.

A factor analysis yielded three scales: GSM Stigma, Confidentiality Concerns, and GSM-Sexual Health Information. Items from the GSM Stigma scale showed that nearly half of respondents had not disclosed their GSM identity to their PCP due to concern about an unaccepting PCP. One-quarter of youth were less inclined to discuss GSM identity and sexual health with their PCP due to concern that their provider would disclose this information to parents; these concerns were greater among adolescents <18 and those not out to parents about their gender identity. Only 25% felt their PCP was helpful about GSM-specific sexual health issues. Youth who were out to parents about their gender identity and had received gender-affirming hormone therapy were more likely to report receiving GSM-specific sexual health information.

READ:  Infidelity perceptions differ between men and women

For the researchers, “trans youth may not discuss their GSM identity or sexual health with PCPs because they anticipate GSM stigma and fear being ‘outed’ to parents.” And so “PCPs should receive transgender-inclusive training to adequately address youths’ sexual health needs and privacy concerns.”

Continue Reading

Health & Wellness

Even with health insurance, lesbian, gay and bi adults more likely to delay medical care

A study shows bisexuals have among the greatest need for regular health care, but are the least likely to get it. And even if they have a high-quality insurance plan through an employer, health equity is far from a reality for many LGBTQ patients.

Published

on

Photo by Marcelo Leal from Unsplash.com

Even when lesbian, gay and bisexual adults have rates of health insurance coverage on par with or better than that of straight men and women, they are still more likely to wait to see the doctor when they need medical care. This is according to a policy brief by the UCLA Center for Health Policy Research

According to Susan H. Babey, a co-author of the study, Disparities in Health Care Access and Health Among lesbians, Gay Men, and Bisexuals in California, one reason cited in other research is that sexual minorities sometimes experience discrimination when they seek health care.

“Sexual minorities who have had a bad experience with a medical provider because of their sexual orientation may try to avoid repeating it,” said Babey, who is also co-director of the Chronic Disease Program at the Center.

The UCLA study looks at differences in access to care, behaviors that negatively affect health (such as smoking or not exercising) and health problems that can result from those behaviors (such as developing hypertension or being overweight), based on people’s sexual orientation. The findings show that 24% of bi men and 22% of straight men say they do not have a doctor they regularly see, compared with only 13% of gay men; but 20% of gay men and 21% of bi men delayed seeking health care in the past year, compared with 13% of straight men.

Thirteen percent of straight women and 15% of lesbians reported that they do not have a doctor they regularly see, while a higher percentage of bisexual women, 22%, said they do not have one. However, 29% of lesbians and bisexual women said they delayed seeking medical care in the past year compared with just 18% of straight women.

READ:  The ultimate low-budget home gym

The study uses data from the combined 2011 to 2014 California Health Interview Survey. Data on transgender people is not included because the survey only began collecting transgender data in 2015-16. More than one million California adults, 4.5% of the state’s adult population, identify as lesbian, gay, homosexual or bi, according to the survey.

Other key findings from the research:

  • Bi people have the worst overall access to a doctor they see on a regular basis and high rates of unhealthy behaviors. Among lesbian/gay, bi and straight adults, bi men and women are the least likely to have a regular source of care, are most likely to delay care and are mostly likely to seek care in an emergency room. Bi men have higher rates of unhealthy behaviors in four of the five categories analyzed in the study. Among women, bi in the study have higher rates of smoking and binge drinking, and are more likely to eat fast food two or more times a week.
  • Gay men report better overall health and fewer behaviors that lead to obesity and hypertension than straight men. Sixty-one percent of gay men said they considered themselves to be in excellent or very good health, compared to 52% of straight men and 44% of bi men. Gay men are less likely to drink sugary beverages daily and were less likely to binge drink than straight and bi men. Twenty-seven percent of straight men in the study were obese, compared with 21% of gay men and 20% of bi men.
  • Straight women have the best access to a doctor they see on a regular basis, overall health and the lowest rates of unhealthy behaviors. Half of straight women said they were in excellent or very good health, versus 44% of lesbians and 45% of bi women. Twenty-seven percent said they had engaged in binge drinking within the previous year, compared to 50% of bi women. Ten percent of straight women were smokers, compared with 23% of bi and lesbian women. Lesbians had the highest rate of obesity, 35%, compared with 26% of  bi women and 24% of straight women.
READ:  Top 10 vegan chocolate desserts in Manila

“Our study shows bisexuals have among the greatest need for regular health care, but are the least likely to get it,” said Joelle Wolstein, a research scientist at the Center and the study’s lead author. “Even if they have a high-quality insurance plan through an employer, health equity is far from a reality for many LGBTQ patients.”

Continue Reading
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement
Advertisement

Facebook

Most Popular