Connect with us

Hi, what are you looking for?

Health & Wellness

Transgender, gender-diverse adults with testosterone therapy had significant decrease in depression, suicidality

Testosterone therapy significantly decreases gender dysphoria, depression, and suicidality in transgender and gender-diverse individuals desiring testosterone therapy.

Testosterone therapy significantly decreases gender dysphoria, depression, and suicidality in transgender and gender-diverse individuals desiring testosterone therapy.

This is according to a study – “Early Access to Testosterone Therapy in Transgender and Gender-Diverse Adults Seeking Masculinization A Randomized Clinical Trial” by Brendan J. Nolan, Sav Zwickl, Peter Locke, et al – that appeared in JAMA Network Open.

A three-month open-label randomized clinical trial was conducted at endocrinology outpatient clinics and primary care clinics specializing in transgender and gender-diverse health in Melbourne, Australia, from November 1, 2021, to July 22, 2022. Participants included transgender and gender-diverse adults aged 18 to 70 years seeking initiation of testosterone therapy.

This study found that – compared with those receiving only standard care – those who received intervention/s had a decrease in gender dysphoria, a clinically significant decrease in depression, and a significant decrease in suicidality.

Resolution of suicidality assessed by PHQ-9 item 9 occurred in 11 individuals (52%) with immediate testosterone commencement compared with one (1 or 5%) receiving standard care.

Seven individuals reported injection site pain/discomfort and one individual reported a transient headache 24 hours following intramuscular administration of testosterone undecanoate. No individual developed polycythemia.

For the researchers, among transgender and gender-diverse adults, “immediate testosterone compared with no treatment significantly reduced gender dysphoria, depression, and suicidality in transgender and gender-diverse individuals desiring testosterone therapy.”

Advertisement. Scroll to continue reading.
Advertisement
Advertisement

Like Us On Facebook

YOU MAY ALSO LIKE

#KaraniwangLGBT

Meet 21-year-old transgender woman Christy, who started sex work when she was 18 or 19. “It was fun,” she said, “because after that, I...

Travel

The rightwing-leaning Supreme Court allowed for the state of Idaho to proceed with the enforcement of a new law that prohibits providing life-saving gender-affirming...

Health & Wellness

The number of self-reported “poor mental health days” per month serves as a reliable indicator of mental health, correlating with other psychological and physical...

Health & Wellness

The evidence on the use of puberty blockers and hormones for children and young people experiencing gender related distress is wholly inadequate, making it...

Advertisement