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Increase in drug-resistant Shigella cases reported among gay and bisexual men

STI Shigella cases continue to occur at high levels among gay, bisexual and other men who have sex with men. Shigella is a gut infection that is spread through bacteria found in feces. It can be passed on during sex, directly or through unwashed hands.

Photo by David Fanuel from Unsplash.com

Sexually transmitted Shigella cases continue to occur at high levels, with 2,560 diagnoses in the UK in 2025 along, which his higher from 2,052 in 2023 and 2,318 in 2024.

This is according to the UK Health Security Agency (UKHSA).

There are several strains of Shigella, with the two most commonly spread through sexual contact among GBMSM the Shigella sonnei and Shigella flexneri.

The UKHSA also reported a serious and growing problem with antibiotic resistance. In 2025, 86% of Shigella sonnei samples, and 94% of Shigella flexneri samples tested showed resistance to antibiotics. Also, more than half of Shigella sonnei cases were extensively drug-resistant (XDR).

According to Dr Katy Sinka, head of STI section at UKSHA: “The rise in sexually transmitted Shigella cases is concerning, but the risks of catching it can be reduced by good hygiene during and after sex and condom use – helping to protect yourself and your partners. It is important that gay and bisexual men do not dismiss their symptoms.”  

Those diagnosed with Shigella may also have been exposed to other STIs, including HIV, so a sexual health screen is recommended.

For GBMSM who have been diagnosed with Shigella, UKSHA recommended: taking time to recover; staying hydrated; avoiding having sex for seven days after the last symptom; avoiding spas, swimming pools, jacuzzis and hot tubs; avoiding sharing towels; and avoiding preparing food for other people.

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